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Attana AB
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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: Quartz Crystal Microbalance Platform for SARS-CoV-2 Immuno-Diagnostics
doi: 10.3390/ijms242316705
Figure Lengend Snippet: SARS-CoV-2 IgG QCM-based immunoassay. ( A ) Schematic representation of assay procedure. The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein is immobilized on an Attana low non-specific binding sensor chip. Human serum is injected (1) and allowed to interact with the immobilized RBD for 120 s, followed by buffer injection for 127 s (2) where only strongly bound antibodies continue to interact. Anti-human-IgG antibodies are injected (3) for the detection of bound IgG antibodies. ( B ) Sensorgram displaying the response in Hertz over time in relation to the events in panel A. The figure shows two samples with varying titers of SARS-CoV-2 anti-IgG.
Article Snippet: The receptor-binding domain of the SARS-CoV-2 S-antigen (RBD-Wuhan, Expres2ion biotechnologies, Hørsholm, Denmark) was immobilized onto an Attana
Techniques: Binding Assay, Injection